The Union for International Cancer Control and the Healthy City Partnership engaged Dalberg to explore and design the Healthy Cities Fund, with the objective of financing city-level health infrastructure in low and middle-income countries. The Dalberg team undertook a market assessment, including desk research and interviews with different health financing experts globally to identify current sources and uses of health infrastructure financing, financing needs and gaps and barriers that inhibit investment. We were then engaged to develop different design options for the fund’s strategy and structure.